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Biochemical characterization of AB-343, a novel, potent, and orally bioavailable SARS-CoV-2...
May 3, 2023 / 0 Minute Read
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May 3, 2023 / 0 Minute Read
Posts for industry: AB-343
March 14, 2023 / 0 Minute Read
A Phase 1a/1b clinical trial evaluating the safety, tolerability, and PK/PD of single and multiple-ascending dose of imdusiran in healthy subjects and patients with cHBV infection.
Preliminary data suggest that imdusiran is generally safe and well tolerated through 48 weeks of dosing and long-term suppression of HBsAg with imdusiran results in increased HBV-specific immune response. Patients who have discontinued all therapy are continuing to be followed.